Loop is about what can be seen and what cannot, how scientists imagine their work and how they describe it. The film is based on the work done in Dr Serge Mostowy’s lab on septin assembly in cells, using a zebrafish model. Lab members describe the intricate sub-cellular septin dynamics and structure. Their explanatory drawings, and discussions with the filmmaker about how they see the research, are incorporated into the animation.

Each person’s unique and idiosyncratic vision of the process brings a different facet to the complex and secret world of septin cytoskeleton dynamics. The scientists’ different theories of assembly reveal the creative and discursive nature of science. The scientists’ original sketches, included at the end of the film, emphasise how closely they worked with the filmmaker to translate their individual vision to the whole.